For further information on how to interpret these results or to get a copy of the MEME software please access http://meme.nbcr.net.
If you use MAST in your research, please cite the following paper:
Timothy L. Bailey and Michael Gribskov,
"Combining evidence using p-values: application to sequence homology searches",
Bioinformatics, 14(1):48-54, 1998.
Inputs |
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The following sequence database was supplied to MAST.
Database | Sequence Count | Residue Count | Last Modified |
---|---|---|---|
adh.s | 33 | 9996 | Wed Jan 11 17:17:32 2012 |
Total | 33 | 9996 |
The following motifs were supplied to MAST from "meme.adh.zoops" last modified on Wed Jan 11 17:17:55 2012.
Similarity | ||||
---|---|---|---|---|
Motif | Width | Best possible match | 1 | 2 |
1 | 21 | GKVVLITGCSSGIGKATAKHL | - | 0.29 |
2 | 29 | SVYCASKFAVRMLTRSMAMEYAPHGIRVN | 0.29 | - |
Search Results |
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Each of the following 33 sequences has an E-value less than
10.
The motif matches shown have a position p-value less than 0.0001.
Click on the arrow (↧) next to the E-value to view more information about a sequence.
Motif 1 |
Motif 2 |
Sequence | E-value | Block Diagram | |
---|---|---|---|
0 100 200 300 400 500 600 700 800 900 |
|||
YRTP_BACSU | 9e-44 | ↧ | |
BUDC_KLETE | 1.1e-42 | ↧ | |
FIXR_BRAJA | 3.8e-37 | ↧ | |
AP27_MOUSE | 2.5e-35 | ↧ | |
NODG_RHIME | 3.2e-34 | ↧ | |
HDHA_ECOLI | 4.1e-34 | ↧ | |
DHGB_BACME | 4.5e-34 | ↧ | |
DHB2_HUMAN | 1.2e-32 | ↧ | |
HDE_CANTR | 1.3e-32 | ↧ | |
DHII_HUMAN | 5e-32 | ↧ | |
DHMA_FLAS1 | 5.4e-32 | ↧ | |
FVT1_HUMAN | 8e-32 | ↧ | |
RIDH_KLEAE | 9.1e-32 | ↧ | |
YINL_LISMO | 1.1e-31 | ↧ | |
2BHD_STREX | 2.4e-31 | ↧ | |
HMTR_LEIMA | 5.5e-31 | ↧ | |
ENTA_ECOLI | 3.6e-30 | ↧ | |
BDH_HUMAN | 4e-30 | ↧ | |
GUTD_ECOLI | 2.2e-29 | ↧ | |
DHES_HUMAN | 3.6e-29 | ↧ | |
BA72_EUBSP | 1.9e-28 | ↧ | |
3BHD_COMTE | 3.1e-28 | ↧ | |
DHB3_HUMAN | 2.6e-27 | ↧ | |
RFBB_NEIGO | 4.3e-25 | ↧ | |
LIGD_PSEPA | 4.3e-25 | ↧ | |
BPHB_PSEPS | 1.3e-24 | ↧ | |
DHCA_HUMAN | 1.5e-22 | ↧ | |
ADH_DROME | 5e-20 | ↧ | |
YURA_MYXXA | 8.4e-20 | ↧ | |
FABI_ECOLI | 1.8e-19 | ↧ | |
PCR_PEA | 2e-14 | ↧ | |
CSGA_MYXXA | 3.9e-13 | ↧ | |
MAS1_AGRRA | 4.2e-13 | ↧ |
Motif 1 |
Motif 2 |
Explanation of MAST Results |
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MAST received the following inputs.
This table summarises the sequence databases specified to MAST.
Summary of the motifs specified to MAST.
This diagram shows the normal spacing of the motifs specified to MAST.
MAST provides the following motif search results.
This table summarises the top scoring sequences with a Sequence E-value better than the threshold (default 10). The sequences are sorted by the Sequence E-value from most to least significant.
Clicking on the ↧ link expands a box below the sequence with additional information and adds two dragable buttons below the block diagram.
MAST scores sequences using the following measures.
The score for the match of a position in a sequence to a motif is computed by by summing the appropriate entry from each column of the position-dependent scoring matrix that represents the motif. Sequences shorter than one or more of the motifs are skipped.
The position p-value of a match is the probability of a single random subsequence of the length of the motif scoring at least as well as the observed match.
The sequence p-value of a score is defined as the probability of a random sequence of the same length containing some match with as good or better a score.
The combined p-value of a sequence measures the strength of the match of the sequence to all the motifs and is calculated by
The E-value of a sequence is the expected number of sequences in a random database of the same size that would match the motifs as well as the sequence does and is equal to the combined p-value of the sequence times the number of sequences in the database.